“Cantaloupe” in the Deep South mostly sounds something like “canna-lope,” without a hint of ‘t’, but Bill Neale saw it spelt “CAN’T ELOPE” on a roadside sign in North Carolina, and a buddy of mine calls them “Romeos and Juliets”.
The name comes from an Italian communi near Rome, one of several Italian towns called “Cantaloupo,” (“song of the wolf” or literally “sings wolf”) where this variety of melon arrived in Europe from (of all places) Armenia in the early 18th century. The cantaloupe didn’t become a commercial crop in the US until the early 20th century. An early popular variety, ‘Rocky Ford’ was developed in Colorado, but ‘Ambrosia’ and ‘El Gordo’ have largely come to dominate the markets.
Incidentally, the European cantaloupe, Cucumis melo var. cantalupensis, is lightly ribbed with a gray-green skin; the American cantaloupe, C. melo var. reticulatus, has a webbed skin. It’s worth noting that the name “musk melon” comes from the pronounced aroma of the uncut fruit; a related group of scentless melons including honeydews, Canary, and Santa Claus are termed inodorata.